Radiation damage is an important factor affecting the life of Reactor Pressure Vessel (RPV). To improve the evaluation performance of Magnetic Barkhausen Noise (MBN) signal detection instrument on the degree of radiation damage, this paper designs a Miniaturized MBN sensor. The sensor is composed of H-shaped silicon steel sheet yoke, excitation coil, detection coil and I-type manganese-zinc ferrite, which can enable the detection instrument to obtain a more stable MBN signal, so as to effectively evaluate the radiation damage of RPV. In addition, the excitation module is simulated and analyzed using the electromagnetic simulation software ANSYS Maxwell, and the effective magnetization area of the specimen is obtained. Finally, through the analysis of the measurement data of the RPV sample, the amplitude and frequency of the optimal excitation signal are determined, which improves the practicability of the MBN detection instrument.