The data structure of telemetry data received by telemetry ground station is complex, there are difficulties in processing telemetry data based on FPGA. Thus the High-Level Synthesis technology is introduced. High-Level Synthesis can shorten FPGA design and development cycle compared to traditional RTL implementation when implementing identical functions. Comparing to RTL implementation, the code size about telemetry data processing is only 1/10 to 1/20, the development cycle is only 1/4 to 1/10, and the code execution efficiency is identical.