The driving and control system of Certain typed LCAC was selected as the research object, an automatic control method based on fuzzy self-tuning PID control is introduced into LCAC course control. Air rudder is chosen as the common control surface of LCAC’s course control. The basic principle of PID course controller is studied and analyzed. According to the control law and experience summary of the parameters of the PID controller, a fuzzy self-tuning PID controller is designed. The specific design steps are given. The tuner can adjust the proportional and differential parameters of the controller in real time in the course control of the LCAC. The simulation results show that the fuzzy self-tuning PID controller can make the course control smoother and no overshoot, shorten the adjusting time of the controller and improve the robustness of the system.