Abstract:: For the control room dispersion, many Data Acquisitions, high labor costs, and difficult management in a thermal power plant of a rubber group, Introduce the design of the management information system , the hardware design and the configuration software design of the host computer based on Siemens S7-1500 PLC and Wincc. PLC establishes distributed I/O to be responsible for data acquisition and data transmission of equipment in seven subsystems of thermal power plant. The field devices in the system are divided into four categories, including Mitsubishi F700 inverter, MODBUS device, analog sensor,digital sensor. Wincc realizes video monitoring, picture monitoring, data storage, data alarm and data query of the system by establishing multi-client mode. The overall communication scheme architecture adopts the PROFIBUS-DP fieldbus communication protocol. The PROFIBUS-DP slave station is established by the ET200SP, and the S7-1500PLC is used as the master station. To ensure stable communication between the master station and the slave station, the optical fiber is used for signal transmission. Siemens-specific communication methods are used between multiple PLCs: one PLC is used as the IO Controller, and the other PLCs are used as IO devices to realize data interaction. The system is stable and reliable. It can reduce the labor cost of enterprises and realize the information management of the system, which has wide application value and development prospects.