Effectiveness evaluation is an indispensable part in spacecraft integral testing and in-orbit flight. For the first moon-earth high-speed reentry flight, an program of flying qualities evaluation was proposed based on mission section. An evaluation index system for moon-earth high-speed reentry is achieved by extracting 7 mission section, 17 constraints including 49 key parameters. A capability quantitative estimation for mission section is established based on the method of quantifying quantitative & qualitative indicators and confirming coefficient with Analytic Hierarchy Process (AHP). It can be used in the problems with quantitative calculation the ability of the aircraft to achieving targets. The new method is applied to moon-earth high-speed reentry spacecraft.