Perception of tactile and slide sensing is an essential function for bionic prosthetic hand. On the basis of original intelligent prostheses, this paper designed an intelligent prosthesis that achieving tactile sensing and slide sensing through the study of tactile and slide sensing methods, those studies included selection of tactile and slide sensor, design of measuring circuit and analysis of the distribution of measuring points, etc.. Further, it achieved the reliable gripping and the adaptive response controlling during maintaining gripping through introducing the fuzzy logic control method. The results showed that this intelligent prostheses achieved stable control of gripping, and fast and precision adaptive respond control while the object sliding.