Abstract:The 4 x 600 MW units in one power plant desulfurization of flue gas continuous emission monitoring system (CEMS) as the background, this paper introduces the lower machine S7-200 PLC and PC Fame View configuration software in the application of CEMS data acquisition and processing subsystem. Expounds the CEMS under a program design principle and function of upper unit state, in view of the actual situation analysis, the optimization program is put forward. Practice proves that the optimized program, can improve the CEMS data reliability and validity. In this paper, the optimization design of CEMS system program was run in a certain electric factory director cycle, the system functions normally, good running characteristics, to achieve the intended purpose.