Abstract:The notable features of the future smart grid is its good interactivity and extensive healing ability, reflecting the level of the technology and intelligence, the development of the national power system. The intelligent distribution network is a core part of the smart grid, it’s two-way interaction with the user, which involves the access problem of a large number distributed power, the distribution network fault recovery reflects complete healing ability, is a multi-target, multi-session, multi-dimensional nonlinear optimization configuration problem, related to the quality of the user's power supply. Multi-Agent technology has unique advantages in terms of computer network self-healing, domestic and foreign scholars have done a lot of research. Introduce multi-Agent immune algorithm into Intelligent distribution network self-healing system, as the AI recovery strategy of distribution network,builded self-healing technique based on multi-Agent distribution network architecture, and through the simulation experiment platform It proved that it is feasible to introduce multi-Agent immune algorithm into self-healing system of the future smart distribution grid.