用于纳米通道单分子检测的数据采集系统的设计与实现[BT)]

Design of Data Acquisition System for Nanopore Single-molecule Detection

摘要:

针对纳米通道单分子检测系统的信号特点和对数据采集的采样精度、采样速率及实时性等要求,设计并实现了基于FPGA和USB2.0接口的数据采集系统;该系统以FPGA作为控制核心,包括数据采集模块、电压输出模块和USB接口电路模块；通过USB2.0接口与计算机连接,实现数据的实时采样和参数的在线配置；此外本系统还采取了低噪声设计;经过相关试验表明,该系统引入的噪声在1 mV内,能够稳定进行数据采集,且采集信号与电压输出信号同步传输,证明该系统能够满足纳米通道单分子检测系统对数据采集的要求。

Abstract:

A data acquisition system based on the FPGA and USB2.0 technology is designed for the nanopore single-molecule detection according to the requirement of the nanopore single-molecule detection system. This system linking pre-amplifier and computer includes data acquisition module, voltage output module and USB interface circuit module, realizing the data real-time sampling and parameters of online configuration. In addition, this system is low-noise design. Tests show that this system is able to acquire data stably, and the noise is controlled with in 1 mV. This system meets the acquirements of nanopore single –molecule detection and worthy of using abroad.